Epiregulin antibody (AA 144-160) (HRP)

Catalog No. ABIN7164655

Product Details anti-Epiregulin Antibody (HRP)

Target: Epiregulin (EREG)

Binding Specificity: AA 144-160

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Epiregulin antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Proepiregulin protein (144-160aa)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Epiregulin

Target: Epiregulin (EREG)

Alternative Name: EREG (EREG Products)

Synonyms: EREG antibody, ER antibody, EPR antibody, proepiregulin antibody, epiregulin antibody, EREG antibody, ereg antibody, Ereg antibody

Background:

Background: Ligand of the EGF receptor/EGFR and ERBB4. Stimulates EGFR and ERBB4 tyrosine phosphorylation (PubMed:9419975). Contributes to inflammation, wound healing, tissue repair, and oocyte maturation by regulating angiogenesis and vascular remodeling and by stimulating cell proliferation (PubMed:24631357).

Aliases: Proepiregulin [Cleaved into: Epiregulin (EPR)], EREG

UniProt: O14944

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation