Neuregulin 2 antibody (AA 112-405)

Catalog No. ABIN7164305

Product Details anti-Neuregulin 2 Antibody

Target: Neuregulin 2 (NRG2)

Binding Specificity: AA 112-405

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neuregulin 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Pro-neuregulin-2, membrane-bound isoform protein (112-405AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Neuregulin 2

Target: Neuregulin 2 (NRG2)

Alternative Name: NRG2 (NRG2 Products)

Synonyms: NRG2 antibody, Don1 antibody, NTAK antibody, DON1 antibody, HRG2 antibody, NTAK_alpha2a antibody, Ntak antibody, neuregulin 2 antibody, NRG2 antibody, Nrg2 antibody

Background:

Background: Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. May also promote the heterodimerization with the EGF receptor.

Aliases: Divergent of neuregulin 1 antibody, Divergent of neuregulin-1 antibody, Don 1 antibody, DON-1 antibody, Neural- and thymus-derived activator for ERBB kinases antibody, Neuregulin 2 antibody, Neuregulin-2 antibody, NRG-2 antibody, Nrg2 antibody, NRG2_HUMAN antibody, NTAK antibody, Pro NRG2 antibody, Pro-NRG2 antibody

UniProt: O14511

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway