PICK1 antibody (AA 1-200) (HRP)
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- Target See all PICK1 Antibodies
- PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))
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Binding Specificity
- AA 1-200
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PICK1 antibody is conjugated to HRP
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Application
- ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human PRKCA-binding protein (1-200AA)
- Isotype
- IgG
- Top Product
- Discover our top product PICK1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))
- Alternative Name
- PICK1 (PICK1 Products)
- Synonyms
- PICK antibody, PRKCABP antibody, Prkcabp antibody, prkcabp antibody, MGC131295 antibody, PICK1 antibody, DKFZp470L2127 antibody, protein interacting with PRKCA 1 antibody, protein interacting with C kinase 1 antibody, protein interacting with PRKCA 1 L homeolog antibody, PICK1 antibody, Pick1 antibody, pick1 antibody, pick1.L antibody
- Background
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Background: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex, the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
Aliases: dJ1039K5 antibody, MGC15204 antibody, OTTHUMP00000028509 antibody, PICK 1 antibody, Pick1 antibody, PICK1_HUMAN antibody, PRKCA binding protein antibody, PRKCA-binding protein antibody, PRKCABP antibody, Protein interacting with C kinase 1 antibody, Protein interacting with PRKCA antibody, Protein interacting with PRKCA 1 antibody, Protein kinase C alpha binding protein antibody, Protein kinase C-alpha-binding protein antibody, Protein that interacts with C kinase 1 antibody
- UniProt
- Q9NRD5
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