PRPF8 antibody (AA 2037-2170) (Biotin)

Catalog No. ABIN7164162

Product Details anti-PRPF8 Antibody (Biotin)

Target: PRPF8 (PRP8 Pre-mRNA Processing Factor 8 (PRPF8))

Binding Specificity: AA 2037-2170

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRPF8 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Pre-mRNA-processing-splicing factor 8 protein (2037-2170AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PRPF8

Target: PRPF8 (PRP8 Pre-mRNA Processing Factor 8 (PRPF8))

Alternative Name: PRPF8 (PRPF8 Products)

Background:

Background: Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both the 5\' and the 3\' splice site.

Aliases: 220 kDa U5 snRNP specific protein antibody, 220 kDa U5 snRNP-specific protein antibody, Apoptosis regulated protein 1 antibody, Apoptosis regulated protein 2 antibody, HPRP8 antibody, p220 antibody, Pre mRNA processing factor 8 antibody, Pre mRNA-processing factor 8, S. cerevisiae, homolog of antibody, Pre-mRNA-processing-splicing factor 8 antibody, Precursor mRNA processing protein antibody, PRP8 antibody, PRP8 homolog antibody, PRP8 pre mRNA processing factor 8 homolog antibody, PRP8_HUMAN antibody, PRPC8 antibody, Prpf8 antibody, Retinitis pigmentosa 13 (autosomal dominant) antibody, RP13 antibody, SNRNP220 antibody, Splicing factor Prp8 antibody, U5 snRNP specific protein antibody, U5 snRNP specific protein (220 kD), ortholog of S. cerevisiae Prp8p antibody

UniProt: Q6P2Q9