PHC1 antibody (AA 142-225) (HRP)

Catalog No. ABIN7163847

Product Details anti-PHC1 Antibody (HRP)

Target: PHC1 (Polyhomeotic-Like 1 (PHC1))

Binding Specificity: AA 142-225

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHC1 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Polyhomeotic-like protein 1 protein (142-225AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PHC1

Target: PHC1 (Polyhomeotic-Like 1 (PHC1))

Alternative Name: PHC1 (PHC1 Products)

Synonyms: EDR1 antibody, HPH1 antibody, RAE28 antibody, AW557034 antibody, Edr antibody, Edr1 antibody, Mph1 antibody, Rae-28 antibody, rae28 antibody, polyhomeotic homolog 1 antibody, polyhomeotic-like 1 (Drosophila) antibody, Phc1 antibody, PHC1 antibody

Background:

Background: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A \'Lys-119\', rendering chromatin heritably changed in its expressibility. Required for proper control of cellular levels of GMNN expression.

Aliases: Early development regulatory protein 1 antibody, hPH1 antibody, mPH1 antibody, PH1 antibody, Phc1 antibody, PHC1_HUMAN antibody, Polyhomeotic-like protein 1 antibody, Rae28 antibody

UniProt: P78364