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PKD1 antibody (AA 615-753)

PKD1 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7163832
  • Target See all PKD1 Antibodies
    PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))
    Binding Specificity
    • 16
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 615-753
    Reactivity
    • 39
    • 26
    • 10
    • 1
    • 1
    Human
    Host
    • 37
    • 1
    • 1
    Rabbit
    Clonality
    • 38
    • 1
    Polyclonal
    Conjugate
    • 14
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PKD1 antibody is un-conjugated
    Application
    • 26
    • 16
    • 15
    • 13
    • 13
    • 7
    • 5
    • 3
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Polycystin-1 protein (615-753AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: IHC:1:500-1:1000, IF:1:200-1:500,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))
    Alternative Name
    PKD1 (PKD1 Products)
    Synonyms
    PBP antibody, Pc-1 antibody, TRPP1 antibody, PC1 antibody, mFLJ00285 antibody, polycystin 1, transient receptor potential channel interacting antibody, polycystin 1, transient receptor poteintial channel interacting antibody, polycystin-1 antibody, PKD1 antibody, Pkd1 antibody, LOC749291 antibody
    Background

    Background: Involved in renal tubulogenesis (PubMed:12482949). Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium (By similarity). Acts as a regulator of cilium length, together with PKD2 (By similarity). The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling (By similarity). The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling (By similarity). May be an ion-channel regulator. Involved in adhesive protein-protein and protein-carbohydrate interactions.

    Aliases: Autosomal dominant polycystic kidney disease 1 protein antibody, Autosomal dominant polycystic kidney disease protein 1 antibody, nPKC-D1 antibody, nPKC-mu antibody, OTTHUMP00000208669 antibody, OTTHUMP00000208670 antibody, PBP antibody, Pc-1 antibody, PKD antibody, Pkd1 antibody, PKD1_HUMAN antibody, Polycystic Kidney Disease 1 antibody, polycystic kidney disease-associated protein antibody, Polycystin 1 Precursor antibody, Polycystin-1 antibody, Protein kinase C mu type antibody, Protein kinase D antibody, Serine/threonine-protein kinase D1 antibody, transient receptor potential cation channel, subfamily P, member 1 antibody, TRPP1 antibody

    UniProt
    P98161
    Pathways
    Myometrial Relaxation and Contraction, Maintenance of Protein Location
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