PKD1L1 antibody (AA 921-1164)

Catalog No. ABIN7163820

Product Details anti-PKD1L1 Antibody

Target: PKD1L1 (Polycystic Kidney Disease 1 Like 1 (PKD1L1))

Binding Specificity: AA 921-1164

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PKD1L1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Polycystic kidney disease protein 1-like 1 protein (921-1164AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PKD1L1

Target: PKD1L1 (Polycystic Kidney Disease 1 Like 1 (PKD1L1))

Alternative Name: PKD1L1 (PKD1L1 Products)

Synonyms: PRO19563 antibody, AA444596 antibody, RGD1564724 antibody, RGD1566034 antibody, polycystin 1 like 1, transient receptor potential channel interacting antibody, polycystic kidney disease 1 like 1 antibody, PKD1L1 antibody, Pkd1l1 antibody

Background:

Background: Component of a ciliary calcium channel that controls calcium concentration within primary cilia without affecting cytoplasmic calcium concentration. Forms a heterodimer with PKD2L1 in primary cilia and forms a calcium-permeant ciliary channel that regulates sonic hedgehog/SHH signaling and GLI2 transcription. Does not constitute the pore-forming subunit. Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD2 in cilia to facilitate flow detection in left/right patterning.

Aliases: PKD1L1 antibody, UNQ5785/PRO19563 antibody, Polycystic kidney disease protein 1-like 1 antibody, PC1-like 1 protein antibody, Polycystin-1L1 antibody

UniProt: Q8TDX9