SUZ12 antibody (AA 131-305)

Catalog No. ABIN7163811

Product Details anti-SUZ12 Antibody

Target: SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

Binding Specificity: AA 131-305

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUZ12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Polycomb protein SUZ12 protein (131-305AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:1000-1:2000, IF:1:50-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SUZ12

Target: SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

Alternative Name: SUZ12 (SUZ12 Products)

Synonyms: fc31h10 antibody, im:7153578 antibody, si:dkey-10p5.2 antibody, suz12 antibody, wu:fc31h10 antibody, 2610028O16Rik antibody, AI195385 antibody, AU016842 antibody, AW536442 antibody, D11Ertd530e antibody, mKIAA0160 antibody, Xsuz12 antibody, chet9 antibody, jjaz1 antibody, CHET9 antibody, ChET 9 protein antibody, JJAZ1 antibody, suz12l antibody, zgc:100863 antibody, SUZ12 polycomb repressive complex 2b subunit antibody, SUZ12 polycomb repressive complex 2 subunit antibody, suppressor of zeste 12 homolog (Drosophila) antibody, SUZ12 polycomb repressive complex 2 subunit S homeolog antibody, SUZ12 polycomb repressive complex 2a subunit antibody, suz12b antibody, Suz12 antibody, SUZ12 antibody, suz12.S antibody, suz12a antibody

Background:

Background: Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates \\\'Lys-9\\\' (H3K9me) and \\\'Lys-27\\\' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.

Aliases: ChET 9 protein antibody, CHET9 antibody, Chromatin precipitated E2F target 9 protein antibody, JJAZ1 antibody, Joined to JAZF1 protein antibody, KIAA0160 antibody, Polycomb protein SUZ12 antibody, Suppressor of zeste 12 homolog antibody, Suppressor of zeste 12 protein homolog antibody, SUZ12 antibody, SUZ12 polycomb repressive complex 2 subunit antibody, SUZ12_HUMAN antibody

UniProt: Q15022