PCGF6 antibody (AA 9-70) (Biotin)

Catalog No. ABIN7163803

Product Details anti-PCGF6 Antibody (Biotin)

Target: PCGF6 (Polycomb Group Ring Finger 6 (PCGF6))

Binding Specificity: AA 9-70

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCGF6 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Polycomb group RING finger protein 6 protein (9-70AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PCGF6

Target: PCGF6 (Polycomb Group Ring Finger 6 (PCGF6))

Alternative Name: PCGF6 (PCGF6 Products)

Synonyms: im:7144322 antibody, si:ch211-67n3.7 antibody, MBLR antibody, RNF134 antibody, 4933407A11Rik antibody, AI604840 antibody, Rnf134 antibody, polycomb group ring finger 6 antibody, PCGF6 antibody, pcgf6 antibody, Pcgf6 antibody

Background:

Background: Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A \'Lys-119\', rendering chromatin heritably changed in its expressibility.

Aliases: MBLR antibody, Mel18 and Bmi1 like RING finger protein antibody, Mel18 and Bmi1-like RING finger antibody, Pcgf6 antibody, PCGF6_HUMAN antibody, Polycomb group RING finger protein 6 antibody, RING finger protein 134 antibody, RNF134 antibody

UniProt: Q9BYE7