PARP3 antibody (AA 1-240)
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- Target See all PARP3 Antibodies
- PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))
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Binding Specificity
- AA 1-240
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PARP3 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Poly [ADP-ribose] polymerase 3 protein (1-240AA)
- Isotype
- IgG
- Top Product
- Discover our top product PARP3 Primary Antibody
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- Application Notes
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))
- Alternative Name
- PARP3 (PARP3 Products)
- Synonyms
- ADPRT-3 antibody, PARP-3 antibody, PM38 antibody, Adprtl3 antibody, fj17c06 antibody, wu:fj17c06 antibody, zgc:66157 antibody, PARP3 antibody, parp3 antibody, ADPRT3 antibody, ADPRTL2 antibody, ADPRTL3 antibody, ARTD3 antibody, IRT1 antibody, PADPRT-3 antibody, A930002C11Rik antibody, AW990611 antibody, Adprt3 antibody, pADPRT-3 antibody, seed maturation protein PM38 antibody, poly (ADP-ribose) polymerase family, member 3 antibody, poly(ADP-ribose) polymerase family member 3 antibody, poly(ADP-ribose) polymerase family member 3 L homeolog antibody, PARP3 antibody, parp3 antibody, parp3.L antibody, Parp3 antibody
- Background
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Background: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.
Aliases: ADP ribosyltransferase (NAD+, poly (ADP ribose) antibody, ADP ribosyltransferase diphtheria toxin like 3 antibody, ADPRT-3 antibody, ADPRT3 antibody, ADPRTL2 antibody, ADPRTL3 antibody, ARTD3 antibody, hPARP 3 antibody, hPARP-3 antibody, hPARP3 antibody, IRT 1 antibody, IRT1 antibody, NAD(+) ADP ribosyltransferase 3 antibody, NAD(+) ADP-ribosyltransferase 3 antibody, NAD+ ADP ribosyltransferase 3 antibody, pADPRT 3 antibody, pADPRT-3 antibody, pADPRT3 antibody, PARP 3 antibody, PARP-3 antibody, PARP3 antibody, PARP3_HUMAN antibody, Poly (ADP ribose) polymerase family, member 3 antibody, Poly (ADP ribose) synthetase 3 antibody, Poly [ADP-ribose] polymerase 3 antibody, Poly[ADP ribose] synthetase 3 antibody, Poly[ADP-ribose] synthase 3 antibody
- UniProt
- Q9Y6F1
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