CYP4F2 antibody (AA 268-373) (Biotin)
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- Target See all CYP4F2 Antibodies
- CYP4F2 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 2 (CYP4F2))
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Binding Specificity
- AA 268-373
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CYP4F2 antibody is conjugated to Biotin
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Application
- ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Phylloquinone omega-hydroxylase CYP4F2 protein (268-373AA)
- Isotype
- IgG
- Top Product
- Discover our top product CYP4F2 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- CYP4F2 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 2 (CYP4F2))
- Alternative Name
- CYP4F2 (CYP4F2 Products)
- Synonyms
- CPF2 antibody, MGC126966 antibody, cytochrome P450 family 4 subfamily F member 2 antibody, cytochrome P450, family 4, subfamily F, polypeptide 2 antibody, cytochrome P450 family 4 subfamily F member 2 L homeolog antibody, CYP4F2 antibody, cyp4f2.L antibody
- Background
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Background: Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:19297519, PubMed:24138531). Also shows arachidonic acid omega-hydroxylase activity in kidney, by mediating conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE), possibly influencing blood pressure control (PubMed:10660572, PubMed:17341693, PubMed:18574070). Also acts as a leukotriene-B(4) omega-hydroxylase by mediating conversion of leukotriene-B(4) (LTB4) to its omega-hydroxylated metabolite 20-hydroxyleukotriene-B(4) (20-OH LTB4) (PubMed:8026587, PubMed:9799565).
Aliases: CYP4F2Cytochrome P450 4F2 antibody, EC 1.14.14.1 antibody, 20-hydroxyeicosatetraenoic acid synthase antibody, 20-HETE synthase antibody, Arachidonic acid omega-hydroxylase antibody, CYPIVF2 antibody, Cytochrome P450-LTB-omega antibody, Docosahexaenoic acid omega-hydroxylase antibody, EC 1.14.14.79 antibody, Leukotriene-B(4) 20-monooxygenase 1 antibody, Leukotriene-B(4) omega-hydroxylase 1 antibody, EC 1.14.14.94 antibody, Phylloquinone omega-hydroxylase CYP4F2 antibody, EC 1.14.14.78 antibody
- UniProt
- P78329
- Pathways
- Monocarboxylic Acid Catabolic Process
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