PAG1 antibody (AA 97-432)

Catalog No. ABIN7163391

Product Details anti-PAG1 Antibody

Target: PAG1 (phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1))

Binding Specificity: AA 97-432

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAG1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 protein (97-432AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PAG1

Target: PAG1 (phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1))

Alternative Name: PAG1 (PAG1 Products)

Synonyms: Cbp antibody, F730007C19Rik antibody, Pag antibody, CBP antibody, PAG antibody, MGC80192 antibody, phosphoprotein associated with glycosphingolipid microdomains 1 antibody, phosphoprotein membrane anchor with glycosphingolipid microdomains 1 antibody, phosphoprotein membrane anchor with glycosphingolipid microdomains 1 L homeolog antibody, Pag1 antibody, PAG1 antibody, pag1.L antibody, pag1 antibody

Background:

Background: Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.

Aliases: CBP antibody, Csk binding protein antibody, Csk-binding protein antibody, FLJ37858 antibody, MGC138364 antibody, PAG 1 antibody, PAG antibody, PAG1 antibody, PAG1_HUMAN antibody, Phosphoprotein associated with glycosphingolipid enriched microdomains 1 antibody, Phosphoprotein associated with glycosphingolipid enriched microdomains antibody, Phosphoprotein associated with glycosphingolipid microdomains 1 antibody, Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 antibody, Protein Associated with Glycosphingolipid Enriched Microdomains antibody, Transmembrane adapter protein PAG antibody, Transmembrane phosphoprotein Cbp antibody

UniProt: Q9NWQ8

Pathways: p53 Signaling, TCR Signaling, EGFR Signaling Pathway, CXCR4-mediated Signaling Events