PREX2 antibody (AA 1417-1592) (HRP)

Catalog No. ABIN7163184

Product Details anti-PREX2 Antibody (HRP)

Target: PREX2 (DEPDC2) (DEP Domain Containing 2 (DEPDC2))

Binding Specificity: AA 1417-1592

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PREX2 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (1417-1592AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PREX2

Target: PREX2 (DEPDC2) (DEP Domain Containing 2 (DEPDC2))

Alternative Name: PREX2 (DEPDC2 Products)

Synonyms: 6230420N16Rik antibody, DEP.2 antibody, DEPDC2 antibody, P-REX2 antibody, AI316880 antibody, AI553603 antibody, C030045D06Rik antibody, D430013K02 antibody, Depdc2 antibody, P-Rex2 antibody, phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 antibody, phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 antibody, PREX2 antibody, Prex2 antibody

Background:

Background: Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.

Aliases: 4 antibody, 5)-dependent Rac exchanger 2 antibody, 5-trisphosphate-dependent Rac exchanger 2 protein antibody, 6230420N16Rik antibody, DEP domain-containing protein 2 antibody, DEP.2 antibody, DEPDC2 antibody, FLJ12987 antibody, P-Rex2 antibody, Phosphatidylinositol 3 antibody, phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 antibody, phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein antibody, phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 antibody, PREX2 antibody, PREX2_HUMAN antibody, PtdIns(3 antibody, PtdIns(3,4,5)-dependent Rac exchanger 2 antibody

UniProt: Q70Z35