PTPMT1 antibody (AA 28-201)

Catalog No. ABIN7163151

Product Details anti-PTPMT1 Antibody

Target: PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))

Binding Specificity: AA 28-201

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPMT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 protein (28-201AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:1000-1:2000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PTPMT1

Target: PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))

Alternative Name: PTPMT1 (PTPMT1 Products)

Synonyms: im:7137979 antibody, zgc:158719 antibody, DUSP23 antibody, MOSP antibody, PLIP antibody, 1110001D10Rik antibody, 2810004N20Rik antibody, Plip antibody, protein tyrosine phosphatase, mitochondrial 1 antibody, PTPMT1 antibody, ptpmt1 antibody, Ptpmt1 antibody

Background:

Background: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells.

Aliases: DUSP23 antibody, FLJ46081 antibody, MOSP antibody, NB4 apoptosis/differentiation related protein antibody, Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 antibody, Phosphoinositide lipid phosphatase antibody, PLIP antibody, PNAS 129 antibody, protein tyrosine phosphatase mitochondrial 1 antibody, Protein-tyrosine phosphatase mitochondrial 1 antibody, pten like phosphatase antibody, PTEN-like phosphatase antibody, PTPM1_HUMAN antibody, Ptpmt1 antibody

UniProt: Q8WUK0

Pathways: Inositol Metabolic Process