PHF21A antibody (AA 312-487) (Biotin)

Catalog No. ABIN7163053

Product Details anti-PHF21A Antibody (Biotin)

Target: PHF21A (PHD Finger Protein 21A (PHF21A))

Binding Specificity: AA 312-487

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHF21A antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human PHD finger protein 21A protein (312-487AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PHF21A

Target: PHF21A (PHD Finger Protein 21A (PHF21A))

Alternative Name: PHF21A (PHF21A Products)

Synonyms: PHF21A antibody, im:7138823 antibody, si:dkey-23n7.9 antibody, BHC80 antibody, RGD1560612 antibody, 80kDa antibody, Bhc antibody, Bhc80 antibody, D030065N23Rik antibody, PFTF1 antibody, fj98d03 antibody, phf21a antibody, wu:fj98d03 antibody, PHD finger protein 21A antibody, PHD finger protein 21Aa antibody, PHD finger protein 21Ab antibody, PHF21A antibody, phf21aa antibody, pf21a antibody, phf21a antibody, LOC100549929 antibody, Phf21a antibody, phf21ab antibody

Background:

Background: Component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it may act as a scaffold. Inhibits KDM1A-mediated demethylation of \'Lys-4\' of histone H3 in vitro, suggesting a role in demethylation regulation.

Aliases: BHC80a antibody, BM-006 antibody, BRAF35-HDAC complex protein BHC80 antibody, BRAF35/HDAC2 complex (80 kDa) antibody, KIAA1696 antibody, PF21A_HUMAN antibody, PHD finger protein 21A antibody, PHF21A antibody

UniProt: Q96BD5

Pathways: Feeding Behaviour