PHF21A antibody (AA 312-487)

Catalog No. ABIN7163052

Product Details anti-PHF21A Antibody

Target: PHF21A (PHD Finger Protein 21A (PHF21A))

Binding Specificity: AA 312-487

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHF21A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human PHD finger protein 21A protein (312-487AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PHF21A

Target: PHF21A (PHD Finger Protein 21A (PHF21A))

Alternative Name: PHF21A (PHF21A Products)

Background:

Background: Component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it may act as a scaffold. Inhibits KDM1A-mediated demethylation of \\\'Lys-4\\\' of histone H3 in vitro, suggesting a role in demethylation regulation.

Aliases: BHC80a antibody, BM-006 antibody, BRAF35-HDAC complex protein BHC80 antibody, BRAF35/HDAC2 complex (80 kDa) antibody, KIAA1696 antibody, PF21A_HUMAN antibody, PHD finger protein 21A antibody, PHF21A antibody

UniProt: Q96BD5

Pathways: Feeding Behaviour