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ETHE1 antibody (AA 8-254)

ETHE1 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7163017
  • Target See all ETHE1 Antibodies
    ETHE1 (Ethylmalonic Encephalopathy 1 (ETHE1))
    Binding Specificity
    • 15
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 8-254
    Reactivity
    • 41
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    Human
    Host
    • 39
    • 2
    Rabbit
    Clonality
    • 41
    Polyclonal
    Conjugate
    • 16
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ETHE1 antibody is un-conjugated
    Application
    • 15
    • 13
    • 13
    • 9
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human, Mouse
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Persulfide dioxygenase ETHE1, mitochondrial protein (8-254AA)
    Isotype
    IgG
    Top Product
    Discover our top product ETHE1 Primary Antibody
  • Application Notes
    Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    ETHE1 (Ethylmalonic Encephalopathy 1 (ETHE1))
    Alternative Name
    ETHE1 (ETHE1 Products)
    Synonyms
    zgc:85680 antibody, HSCO antibody, YF13H12 antibody, 0610025L15Rik antibody, Hsco antibody, ETHE1, persulfide dioxygenase antibody, ethylmalonic encephalopathy 1 antibody, Ethe1 antibody, ethe1 antibody, ETHE1 antibody
    Background

    Background: Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H(2)S) is first oxidized by SQRDL, giving rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide, once it has been transferred to a thiophilic acceptor, such as glutathione (R-SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H(2)S levels that have toxic effects, due to the inhibition of cytochrome c oxidase. First described as a protein that can shuttle between the nucleus and the cytoplasm and suppress p53-induced apoptosis by sequestering the transcription factor RELA/NFKB3 in the cytoplasm and preventing its accumulation in the nucleus (PubMed:12398897).

    Aliases: Ethe1 antibody, ETHE1 protein, mitochondrial precursor antibody, ETHE1_HUMAN antibody, ethylmalonic encephalopathy 1 antibody, Ethylmalonic encephalopathy protein 1 antibody, hepatoma subtracted clone one antibody, Hepatoma subtracted clone one protein antibody, HSCO antibody, mitochondrial antibody, Protein ETHE1 antibody, Protein ETHE1 mitochondrial antibody, YF13H12 antibody

    UniProt
    O95571
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