FKBP8 antibody (AA 58-190)

Catalog No. ABIN7162843

Product Details anti-FKBP8 Antibody

Target: FKBP8 (FK506 Binding Protein 8, 38kDa (FKBP8))

Binding Specificity: AA 58-190

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKBP8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP8 protein (58-190AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FKBP8

Target: FKBP8 (FK506 Binding Protein 8, 38kDa (FKBP8))

Alternative Name: FKBP8 (FKBP8 Products)

Synonyms: FKBP8 antibody, fkbp8 antibody, 38kDa antibody, FKBP-38 antibody, FKBP-8 antibody, Fkbp38 antibody, zgc:77672 antibody, FKBP38 antibody, FKBPr38 antibody, FK506 binding protein 8 antibody, FK506 binding protein 8 L homeolog antibody, FKBP8 antibody, fkbp8 antibody, Fkbp8 antibody, fkbp8.L antibody

Background:

Background: Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.

Aliases: 38 kDa FK506-binding protein antibody, 38 kDa FKBP antibody, 38 kDa antibody, FK506 binding protein 8 antibody, FK506 binding protein 8, 38 kDa antibody, FK506 binding protein, 38 kDa antibody, FK506-binding protein 8 antibody, FKBP 38 antibody, FKBP-38 antibody, FKBP-8 antibody, Fkbp8 antibody, FKBP8_HUMAN antibody, FKBPR38 antibody, hFKBP38 antibody, Peptidyl-prolyl cis-trans isomerase FKBP8 antibody, PPIase FKBP8 antibody, Rotamase antibody, Sam11 antibody

UniProt: Q14318

Pathways: Autophagy