PAM antibody (AA 338-497)

Catalog No. ABIN7162786

Product Details anti-PAM Antibody

Target: PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))

Binding Specificity: AA 338-497

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAM antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Peptidyl-glycine alpha-amidating monooxygenase protein (338-497AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PAM

Target: PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))

Alternative Name: PAM (PAM Products)

Synonyms: PAL antibody, PHM antibody, pal antibody, phm antibody, pamb antibody, CG3832 antibody, Dmel\\CG3832 antibody, dPHM antibody, AE-I antibody, PAL-A antibody, PHM-A antibody, pama antibody, si:dkeyp-35f12.2 antibody, peptidylglycine alpha-amidating monooxygenase antibody, peptidylglycine alpha-amidating monooxygenase S homeolog antibody, Peptidylglycine-alpha-hydroxylating monooxygenase antibody, peptidylglycine alpha-amidating monooxygenase L homeolog antibody, PAM antibody, Pam antibody, pam.S antibody, CHLREDRAFT_150435 antibody, sce7070 antibody, pam antibody, Phm antibody, pam.L antibody

Background:

Background: Bifunctional enzyme that catalyzes 2 sequential steps in C-terminal alpha-amidation of peptides. The monooxygenase part produces an unstable peptidyl(2-hydroxyglycine) intermediate that is dismutated to glyoxylate and the corresponding desglycine peptide amide by the lyase part. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity.

Aliases: AMD_HUMAN antibody, PAL antibody, PAM antibody, Pancreatic peptidylglycine alpha amidating monooxygenase antibody, Peptidyl alpha amidating enzyme antibody, Peptidyl alpha hydroxyglycine alpha amidating lyase antibody, Peptidyl-alpha-hydroxyglycine alpha-amidating lyase antibody, Peptidylamidoglycolate lyase antibody, Peptidylglycine 2 hydroxylase antibody, Peptidylglycine alpha amidating monooxygenase antibody, Peptidylglycine alpha hydroxylating monooxygenase antibody, PHM antibody

UniProt: P19021