PASK antibody (AA 482-602) (Biotin)

Catalog No. ABIN7162685

Product Details anti-PASK Antibody (Biotin)

Target: PASK (PAS Domain Containing Serine/threonine Kinase (PASK))

Binding Specificity: AA 482-602

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PASK antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human PAS domain-containing serine/threonine-protein kinase protein (482-602AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PASK

Target: PASK (PAS Domain Containing Serine/threonine Kinase (PASK))

Alternative Name: PASK (PASK Products)

Synonyms: pas antibody, wu:fb69h07 antibody, PASK antibody, PASKIN antibody, STK37 antibody, mKIAA0135 antibody, PAS domain containing serine/threonine kinase antibody, Pask antibody, pask antibody, PASK antibody

Background:

Background: Serine/threonine-protein kinase involved in energy homeostasis and protein translation. Phosphorylates EEF1A1, GYS1, PDX1 and RPS6. Probably plays a role under changing environmental conditions (oxygen, glucose, nutrition), rather than under standard conditions. Acts as a sensor involved in energy homeostasis: regulates glycogen synthase synthesis by mediating phosphorylation of GYS1, leading to GYS1 inactivation. May be involved in glucose-stimulated insulin production in pancreas and regulation of glucagon secretion by glucose in alpha cells, however such data require additional evidences. May play a role in regulation of protein translation by phosphorylating EEF1A1, leading to increase translation efficiency. May also participate to respiratory regulation.

Aliases: DKFZP434O051 antibody, DKFZp686P2031 antibody, hPASK antibody, KIAA0135 antibody, MGC93882 antibody, mKIAA0135 antibody, PAS domain containing serine/threonine kinase antibody, PAS domain containing serine/threonine protein kinase antibody, PAS domain-containing serine/threonine-protein kinase antibody, PAS kinase antibody, PAS serine/threonine kinase antibody, PAS-kinase antibody, Pask antibody, PASK_HUMAN antibody, PASKIN antibody, STK 37 antibody, STK37 antibody

UniProt: Q96RG2

Pathways: Regulation of Carbohydrate Metabolic Process