PARD3 antibody (AA 1068-1356)

Catalog No. ABIN7162659

Product Details anti-PARD3 Antibody

Target: PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

Binding Specificity: AA 1068-1356

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARD3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Partitioning defective 3 homolog protein (1068-1356AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:100-1:1000, IF:1:50-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PARD3

Target: PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

Alternative Name: PARD3 (PARD3 Products)

Background:

Background: Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.

Aliases: agouti signaling protein antibody, ASIP antibody, Atypical PKC isotype specific interacting protein antibody, Atypical PKC isotype-specific-interacting protein antibody, Baz antibody, bazooka antibody, Coagulation factor II receptor-like 2 antibody, CTCL tumor antigen se2-5 antibody, F2rl2 antibody, PAR-3 antibody, par-3 family cell polarity regulator alpha antibody, par-3 family cell polarity regulator antibody, PAR3 alpha antibody, par3 antibody, PAR3-alpha antibody, PARD-3 antibody, Pard3 antibody, PARD3_HUMAN antibody, PARD3A antibody, Partitioning defective 3 homolog antibody, Partitioning-defective 3 homolog antibody, Partitioning-defective protein 3, C. elegans, homolog of antibody, SE2-5L16 antibody, SE2-5LT1 antibody, SE2-5T2 antibody, Thrombin receptor-like 2 antibody

UniProt: Q8TEW0

Pathways: Cell-Cell Junction Organization