NOTUM antibody (AA 100-235) (Biotin)

Catalog No. ABIN7162528

Product Details anti-NOTUM Antibody (Biotin)

Target: NOTUM (Notum Pectinacetylesterase Homolog (NOTUM))

Binding Specificity: AA 100-235

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOTUM antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Palmitoleoyl-protein carboxylesterase NOTUM protein (100-235AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NOTUM

Target: NOTUM (Notum Pectinacetylesterase Homolog (NOTUM))

Alternative Name: NOTUM (NOTUM Products)

Synonyms: 5730593N15Rik antibody, RGD1307119 antibody, notum, palmitoleoyl-protein carboxylesterase antibody, notum pectinacetylesterase homolog (Drosophila) antibody, NOTUM, palmitoleoyl-protein carboxylesterase antibody, NOTUM antibody, Notum antibody

Background:

Background: Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleylation of WNT proteins. Serine palmitoleylation of WNT proteins is required for efficient binding to frizzled receptors (PubMed:25731175).

Aliases: NOTUM antibody, notum pectinacetylesterase homolog (Drosophila) antibody, Notum pectinacetylesterase homolog antibody, NOTUM_HUMAN antibody, Protein notum homolog antibody

UniProt: Q6P988