PAX6 antibody (AA 1-300)

Catalog No. ABIN7162504

Product Details anti-PAX6 Antibody

Target: PAX6 (Paired Box 6 (PAX6))

Binding Specificity: AA 1-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAX6 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Paired box protein Pax-6 protein (1-300AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PAX6

Target: PAX6 (Paired Box 6 (PAX6))

Alternative Name: PAX6 (PAX6 Products)

Background:

Background: Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes.

Aliases: AN 2 antibody, AN antibody, AN2 antibody, Aniridia type II protein antibody, D11S812E antibody, FVH1 antibody, KIAA0552 antibody, Leucine zipper putative tumor suppressor 3 antibody, LZTS3 antibody, MGC17209 antibody, MGDA antibody, Oculorhombin antibody, Paired box 6 antibody, Paired box gene 6 (aniridia keratitis) antibody, Paired Box Gene 6 antibody, Paired box homeotic gene 6 antibody, Paired box protein Pax-6 antibody, Paired box protein Pax6 antibody, PAX 6 antibody, PAX6 antibody, PAX6_HUMAN antibody, ProSAP-interacting protein 1 antibody, PROSAPIP1 antibody, Sey antibody, WAGR antibody

UniProt: P26367

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis