SIN3B antibody (AA 705-769)
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- Target See all SIN3B Antibodies
- SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))
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Binding Specificity
- AA 705-769
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SIN3B antibody is un-conjugated
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Application
- ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Paired amphipathic helix protein Sin3b protein (705-769AA)
- Isotype
- IgG
- Top Product
- Discover our top product SIN3B Primary Antibody
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- Application Notes
- Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))
- Alternative Name
- SIN3B (SIN3B Products)
- Synonyms
- fj63d08 antibody, si:dkey-6n6.6 antibody, wu:fj63d08 antibody, 2810430C10Rik antibody, SIN3 transcription regulator family member B antibody, SIN3 transcription regulator family member B S homeolog antibody, transcriptional regulator, SIN3B (yeast) antibody, sin3b antibody, SIN3B antibody, sin3b.S antibody, Sin3b antibody
- Background
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Background: Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression.
Aliases: SIN3B antibody, KIAA0700 antibody, Paired amphipathic helix protein Sin3b antibody, Histone deacetylase complex subunit Sin3b antibody, Transcriptional corepressor Sin3b antibody
- UniProt
- O75182
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