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SIN3A antibody (AA 1-123)

SIN3A Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7162483
  • Target See all SIN3A Antibodies
    SIN3A (SIN3 homolog A, transcription regulator (SIN3A))
    Binding Specificity
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-123
    Reactivity
    • 43
    • 39
    • 26
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 52
    • 2
    • 1
    Rabbit
    Clonality
    • 44
    • 11
    Polyclonal
    Conjugate
    • 27
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SIN3A antibody is un-conjugated
    Application
    • 35
    • 20
    • 9
    • 9
    • 9
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Paired amphipathic helix protein Sin3a protein (1-123AA)
    Isotype
    IgG
    Top Product
    Discover our top product SIN3A Primary Antibody
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    SIN3A (SIN3 homolog A, transcription regulator (SIN3A))
    Alternative Name
    SIN3A (SIN3A Products)
    Synonyms
    AW553200 antibody, Sin3 antibody, mKIAA4126 antibody, mSin3A antibody, zgc:162128 antibody, SIN3A antibody, SIN3 transcription regulator family member A antibody, transcriptional regulator, SIN3A (yeast) antibody, paired amphipathic helix protein Sin3a antibody, SIN3 transcription regulator family member Aa antibody, SIN3A antibody, Sin3a antibody, LOC100641919 antibody, sin3aa antibody, LOC100439524 antibody
    Background

    Background: Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in he control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation. Cooperates with FOXK1 to regulate cell cycle progression probably by repressing cell cycle inhibitor genes expression (By similarity).

    Aliases: AW553200 antibody, DKFZP434K2235 antibody, FLJ90319 antibody, Histone deacetylase complex subunit Sin 3a antibody, Histone deacetylase complex subunit Sin3a antibody, KIAA0700 antibody, Kiaa4126 antibody, mKIAA4126 antibody, Paired amphipathic helix protein Sin 3a antibody, Paired amphipathic helix protein Sin3a antibody, Sin 3a antibody, SIN3 homolog A antibody, SIN3 homolog A transcription regulator (yeast) antibody, SIN3 homolog A transcription regulator antibody, SIN3 transcription regulator homolog A antibody, Sin3a antibody, SIN3A protein antibody, SIN3A_HUMAN antibody, Transcriptional co repressor Sin 3A antibody, Transcriptional co repressor Sin3A antibody, Transcriptional corepressor Sin3a antibody, Transcriptional regulator SIN3A antibody

    UniProt
    Q96ST3
    Pathways
    Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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