NR1H2 antibody (AA 1-461)
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- Target See all NR1H2 Antibodies
- NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))
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Binding Specificity
- AA 1-461
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NR1H2 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Oxysterols receptor LXR-beta protein (1-461AA)
- Isotype
- IgG
- Top Product
- Discover our top product NR1H2 Primary Antibody
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- Application Notes
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))
- Alternative Name
- NR1H2 (NR1H2 Products)
- Synonyms
- NR1H2 antibody, lxr-b antibody, lxrb antibody, ner antibody, ner-i antibody, rip15 antibody, unr antibody, DKFZp468A0622 antibody, AI194859 antibody, LXR antibody, LXRB antibody, LXRbeta antibody, NER1 antibody, OR-1 antibody, RIP15 antibody, UR antibody, Unr antibody, Unr2 antibody, LXR-b antibody, NER antibody, NER-I antibody, UNR antibody, nuclear receptor subfamily 1 group H member 2 antibody, nuclear receptor subfamily 1, group H, member 2 antibody, nuclear receptor subfamily 1 group H member 2 L homeolog antibody, NR1H2 antibody, nr1h2 antibody, Nr1h2 antibody, nr1h2.L antibody
- Background
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Background: Nuclear receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5\'-AGGTCA-3\' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8, DLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity). Exhibits a ligand-dependent transcriptional activation activity (PubMed:25661920).
Aliases: Liver X nuclear receptor beta antibody, Liver X receptor beta antibody, LX receptor beta antibody, LXR b antibody, LXR beta antibody, LXRB antibody, NER antibody, NER I antibody, NER1 antibody, NR1H 2 antibody, NR1H2 antibody, NR1H2_HUMAN antibody, Nuclear orphan receptor LXR beta antibody, Nuclear receptor NER antibody, Nuclear receptor subfamily 1 group H member 2 antibody, OR-1 antibody, Oxysterols receptor LXR-beta antibody, RIP15 antibody, Steroid hormone nuclear receptor NER antibody, Ubiquitously-expressed nuclear receptor antibody, UNR antibody
- UniProt
- P55055
- Pathways
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding
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