OAZ1 antibody (AA 1-68)

Catalog No. ABIN7162292

Product Details anti-OAZ1 Antibody

Target: OAZ1 (Ornithine Decarboxylase Antizyme 1 (OAZ1))

Binding Specificity: AA 1-68

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OAZ1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Ornithine decarboxylase antizyme 1 protein (1-68AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for OAZ1

Target: OAZ1 (Ornithine Decarboxylase Antizyme 1 (OAZ1))

Alternative Name: OAZ1 (OAZ1 Products)

Synonyms: AZI antibody, OAZ antibody, AZ-1 antibody, AZ1 antibody, Antizyme antibody, ODC-Az antibody, Oaz antibody, ODCAC antibody, oaz antibody, AZS antibody, oaz1 antibody, ornithine decarboxylase antizyme 1 antibody, ornithine decarboxylase antizyme 1 S homeolog antibody, ornithine decarboxylase antizyme 1a antibody, OAZ1 antibody, Oaz1 antibody, oaz1.S antibody, oaz1a antibody

Background:

Background: Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake by binding to and targeting ODC1 for degradation (PubMed:17900240). Stabilizes AZIN2 by interfering with its ubiquitination. Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. Involved in the translocation of AZNI2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol.

Aliases: Antizyme 1 antibody, Antizyme antibody, AZI antibody, MGC138338 antibody, OAZ 1 antibody, OAZ antibody, OAZ1 antibody, OAZ1_HUMAN antibody, ODC Az antibody, ODC-Az antibody, Ornithine decarboxylase antizyme 1 antibody, Ornithine decarboxylase antizyme antibody

UniProt: P54368