ORC4 antibody (AA 1-436)

Catalog No. ABIN7162269

Product Details anti-ORC4 Antibody

Target: ORC4 (Origin Recognition Complex, Subunit 4 (ORC4))

Binding Specificity: AA 1-436

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ORC4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Origin recognition complex subunit 4 protein (1-436AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ORC4

Target: ORC4 (Origin Recognition Complex, Subunit 4 (ORC4))

Alternative Name: ORC4 (ORC4 Products)

Synonyms: ORC4L antibody, ORC4P antibody, Orc4P antibody, Orc4l antibody, mMmORC4 antibody, CG2917 antibody, DmORC4 antibody, Dmel\\CG2917 antibody, ORC antibody, ORC4 antibody, dmOrc4 antibody, orc4 antibody, rDmORC antibody, orc4l antibody, fc50c03 antibody, wu:fc50c03 antibody, zgc:85772 antibody, ATORC4 antibody, F23H14.9 antibody, F23H14_9 antibody, ORIGIN RECOGNITION COMPLEX SUBUNIT 4 antibody, origin recognition complex subunit 4 antibody, origin recognition complex subunit 4 antibody, origin recognition complex, subunit 4 antibody, Origin recognition complex subunit 4 antibody, origin recognition complex subunit 4 L homeolog antibody, origin recognition complex subunit Orc4 antibody, ORC4 antibody, Orc4 antibody, orc4.L antibody, orc4 antibody, CNM01830 antibody

Background:

Background: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.

Aliases: cognition complex, subunit 4, S. cerevisiae, homolog of antibody, FLJ46668 antibody, HSORC4 antibody, ORC 4 antibody, ORC 4L antibody, ORC 4P antibody, ORC4 antibody, ORC4_HUMAN antibody, ORC4L antibody, ORC4L protein antibody, ORC4P antibody, Origin recognition complex subunit 4 (yeast homolog) like antibody, Origin recognition complex subunit 4 antibody, Origin recognition complex subunit 4 like (yeast) antibody, Origin recognition complex subunit 4 like antibody, origin recognition complex, subunit 4 homolog antibody, Origin recognition complex, subunit 4, S. cerevisiae, homolog-like antibody

UniProt: O43929

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA