OFD1 antibody (AA 598-771) (Biotin)

Catalog No. ABIN7162254

Product Details anti-OFD1 Antibody (Biotin)

Target: OFD1 (Oral-Facial-Digital Syndrome 1 (OFD1))

Binding Specificity: AA 598-771

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OFD1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Oral-facial-digital syndrome 1 protein (598-771AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for OFD1

Target: OFD1 (Oral-Facial-Digital Syndrome 1 (OFD1))

Alternative Name: OFD1 (OFD1 Products)

Synonyms: 71-7A antibody, CXorf5 antibody, JBTS10 antibody, RP23 antibody, SGBS2 antibody, RGD1562231 antibody, OFD1, centriole and centriolar satellite protein antibody, OFD1 antibody, ofd1 antibody, Ofd1 antibody

Background:

Background: Component of the centrioles controlling mother and daughter centrioles length. Recruits to the centriole IFT88 and centriole distal appendage-specific proteins including CEP164. Involved in the biogenesis of the cilium, a centriole-associated function. The cilium is a cell surface projection found in many vertebrate cells required to transduce signals important for development and tissue homeostasis. Plays an important role in development by regulating Wnt signaling and the specification of the left-right axis. Only OFD1 localized at the centriolar satellites is removed by autophagy, which is an important step in the ciliogenesis regulation (By similarity).

Aliases: 71 7A antibody, 717A antibody, CXorf5 antibody, JBTS10 antibody, Ofd1 antibody, OFD1_HUMAN antibody, oral facial digital syndrome 1 antibody, Oral-facial-digital syndrome 1 protein antibody, OTTHUMP00000022941 antibody, Protein 71-7A antibody, RGD1562231 antibody, SGBS2 antibody

UniProt: O75665

Pathways: M Phase