Oligophrenin 1 antibody (AA 1-270)
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- Target See all Oligophrenin 1 (OPHN1) Antibodies
- Oligophrenin 1 (OPHN1)
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Binding Specificity
- AA 1-270
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Oligophrenin 1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Cross-Reactivity
- Human
- Purification
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Oligophrenin-1 protein (1-270AA)
- Isotype
- IgG
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- Application Notes
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- Oligophrenin 1 (OPHN1)
- Alternative Name
- OPHN1 (OPHN1 Products)
- Background
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Background: Stimulates GTP hydrolysis of members of the Rho family. Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in synaptic function. Critical for the stabilization of AMPA receptors at postsynaptic sites. Critical for the regulation of synaptic vesicle endocytosis at presynaptic terminals. Required for the localization of NR1D1 to dendrites, can suppress its repressor activity and protect it from proteasomal degradation (By similarity).
Aliases: OPHN1 antibody, Oligophrenin-1 antibody
- UniProt
- O60890
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