NUP62 antibody (AA 173-522)

Catalog No. ABIN7161836

Product Details anti-NUP62 Antibody

Target: NUP62 (Nucleoporin 62kDa (NUP62))

Binding Specificity: AA 173-522

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP62 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Nuclear pore glycoprotein p62 protein (173-522AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IP:1:200-1:2000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NUP62

Target: NUP62 (Nucleoporin 62kDa (NUP62))

Alternative Name: NUP62 (NUP62 Products)

Background:

Background: Essential component of the nuclear pore complex (PubMed:1915414). The N-terminal is probably involved in nucleocytoplasmic transport (PubMed:1915414). The C-terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex (PubMed:1915414, PubMed:24107630). Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation (PubMed:24107630). It might be involved in protein recruitment to the centrosome after nuclear breakdown (PubMed:24107630).

Aliases: NUP62 antibody, Nuclear pore glycoprotein p62 antibody, 62 kDa nucleoporin antibody, Nucleoporin Nup62 antibody

UniProt: P37198

Pathways: EGFR Signaling Pathway, SARS-CoV-2 Protein Interactome