NUP62 antibody (AA 173-522)

Catalog No. ABIN7161836

Product Details anti-NUP62 Antibody

Target: NUP62 (Nucleoporin 62kDa (NUP62))

Binding Specificity: AA 173-522

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP62 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Nuclear pore glycoprotein p62 protein (173-522AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IP:1:200-1:2000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NUP62

Target: NUP62 (Nucleoporin 62kDa (NUP62))

Alternative Name: NUP62 (NUP62 Products)

Synonyms: IBSN antibody, SNDI antibody, p62 antibody, NUP62 antibody, AA589433 antibody, AI426861 antibody, AI790512 antibody, AU045898 antibody, D7Ertd649e antibody, Nupc1 antibody, CG6251 antibody, Dmel\\CG6251 antibody, DDBDRAFT_0167902 antibody, DDBDRAFT_0237712 antibody, DDB_0167902 antibody, DDB_0237712 antibody, nup62 antibody, Np62 antibody, nucleoporin 62 antibody, hypothetical protein antibody, nucleoporin 62kDa antibody, Nucleoporin 62kD antibody, predicted protein antibody, nuclear pore protein antibody, Nup62 nuclear pore complex glycoprotein p62-related protein (IC) antibody, Nuclear pore glycoprotein p62 antibody, NUP62 antibody, PGTG_03077 antibody, Nup62 antibody, nup62 antibody

Background:

Background: Essential component of the nuclear pore complex (PubMed:1915414). The N-terminal is probably involved in nucleocytoplasmic transport (PubMed:1915414). The C-terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex (PubMed:1915414, PubMed:24107630). Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation (PubMed:24107630). It might be involved in protein recruitment to the centrosome after nuclear breakdown (PubMed:24107630).

Aliases: NUP62 antibody, Nuclear pore glycoprotein p62 antibody, 62 kDa nucleoporin antibody, Nucleoporin Nup62 antibody

UniProt: P37198

Pathways: EGFR Signaling Pathway, SARS-CoV-2 Protein Interactome