C8orf80 antibody (AA 1-228) (Biotin)

Catalog No. ABIN7161802

Product Details anti-C8orf80 Antibody (Biotin)

Target: C8orf80 (NUGGC) (Nuclear GTPase, Germinal Center Associated (NUGGC))

Binding Specificity: AA 1-228

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C8orf80 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Nuclear GTPase SLIP-GC protein (1-228AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for C8orf80

Target: C8orf80 (NUGGC) (Nuclear GTPase, Germinal Center Associated (NUGGC))

Alternative Name: NUGGC (NUGGC Products)

Synonyms: C8orf80 antibody, SLIP-GC antibody, nuclear GTPase, germinal center associated antibody, NUGGC antibody

Background:

Background: Nuclear GTPase found in germinal center B-cells, where it may inhibit function of the activation-induced cytidine deaminase AICDA (PubMed:19734146). Reduces somatic hypermutation in B-cells which may enhance genome stability (By similarity).

Aliases: NUGGC antibody, C8orf80 antibody, HMFN0672 antibody, Nuclear GTPase SLIP-GC antibody, EC 3.6.1.- antibody, Speckled-like pattern in the germinal center antibody

UniProt: Q68CJ6