GBA2 antibody (AA 656-867) (Biotin)

Catalog No. ABIN7161687

Product Details anti-GBA2 Antibody (Biotin)

Target: GBA2 (Glucosidase, beta (Bile Acid) 2 (GBA2))

Binding Specificity: AA 656-867

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBA2 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Non-lysosomal glucosylceramidase protein (656-867AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GBA2

Target: GBA2 (Glucosidase, beta (Bile Acid) 2 (GBA2))

Alternative Name: GBA2 (GBA2 Products)

Synonyms: TLN1 antibody, F630034E04 antibody, SPG46 antibody, talin 1 antibody, glucosidase, beta (bile acid) 2 antibody, glucosylceramidase beta 2 antibody, glucosidase beta 2 antibody, TLN1 antibody, gba2 antibody, GBA2 antibody, Gba2 antibody

Background:

Background: Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide (GlcCer) to free glucose and ceramide. Involved in sphingomyelin generation and prevention of glycolipid accumulation. May also catalyze the hydrolysis of bile acid 3-O-glucosides, however, the relevance of such activity is unclear in vivo. Plays a role in central nevous system development. Required for proper formation of motor neuron axons.

Aliases: GBA2 antibody, KIAA1605 antibody, SPG46 antibody, AD035Non-lysosomal glucosylceramidase antibody, NLGase antibody, EC 3.2.1.45 antibody, Beta-glucocerebrosidase 2 antibody, Beta-glucosidase 2 antibody, Bile acid beta-glucosidase GBA2 antibody, Bile acid glucosyl transferase GBA2 antibody, Cholesterol glucosyltransferase GBA2 antibody, EC 2.4.1.- antibody, Cholesteryl-beta-glucosidase GBA2 antibody, EC 3.2.1.104 antibody, Glucosylceramidase 2 antibody

UniProt: Q9HCG7