NHEJ1 antibody (AA 225-296) (Biotin)

Catalog No. ABIN7161683

Product Details anti-NHEJ1 Antibody (Biotin)

Target: NHEJ1 (Nonhomologous End-Joining Factor 1 (NHEJ1))

Binding Specificity: AA 225-296

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NHEJ1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Non-homologous end-joining factor 1 protein (225-296AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NHEJ1

Target: NHEJ1 (Nonhomologous End-Joining Factor 1 (NHEJ1))

Alternative Name: NHEJ1 (NHEJ1 Products)

Synonyms: NHEJ1 antibody, zgc:85657 antibody, XLF antibody, 1700029B21Rik antibody, cernunnos antibody, non-homologous end joining factor 1 antibody, non-homologous end joining factor 1 S homeolog antibody, solute carrier family 23 member 3 antibody, nonhomologous end-joining factor 1 antibody, NHEJ1 antibody, nhej1.S antibody, nhej1 antibody, SLC23A3 antibody, Nhej1 antibody

Background:

Background: DNA repair protein involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. May serve as a bridge between XRCC4 and the other NHEJ factors located at DNA ends, or may participate in reconfiguration of the end bound NHEJ factors to allow XRCC4 access to the DNA termini. It may act in concert with XRCC6/XRCC5 (Ku) to stimulate XRCC4-mediated joining of blunt ends and several types of mismatched ends that are noncomplementary or partially complementary (PubMed:16439204, PubMed:16439205, PubMed:17470781). Binds DNA in a length-dependent manner (PubMed:17317666).

Aliases: Cernunnos antibody, FLJ12610 antibody, NHEJ 1 antibody, Nhej1 antibody, NHEJ1, S. cerevisiae, homolog of antibody, NHEJ1_HUMAN antibody, Non homologous end joining factor 1 antibody, Non-homologous end-joining factor 1 antibody, Nonhomologous end joining factor 1 antibody, OTTHUMP00000164168 antibody, OTTHUMP00000206275 antibody, OTTHUMP00000206279 antibody, Protein cernunnos antibody, XLF antibody, XRCC4 like factor antibody, XRCC4-like factor antibody

UniProt: Q9H9Q4

Pathways: DNA Damage Repair