NOG antibody (AA 28-232)

Catalog No. ABIN7161677

Product Details anti-NOG Antibody

Target: NOG (Noggin (NOG))

Binding Specificity: AA 28-232

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOG antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Noggin protein (28-232AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NOG

Target: NOG (Noggin (NOG))

Alternative Name: NOG (NOG Products)

Background:

Background: Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. Essential for cartilage morphogenesis and joint formation. Inhibits chondrocyte differentiation through its interaction with GDF5 and, probably, GDF6 (PubMed:21976273, PubMed:26643732).

Aliases: Nog antibody, NOGG_HUMAN antibody, Noggin antibody, SYM 1 antibody, SYM1 antibody, Symphalangism 1 (proximal) antibody, Synostoses (multiple) syndrome 1 antibody, SYNS 1 antibody, SYNS1 antibody

UniProt: Q13253

Pathways: Stem Cell Maintenance, Tube Formation