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NMRAL1 antibody (AA 1-299) (FITC)

NMRAL1 Reactivity: Human Host: Rabbit Polyclonal FITC
Catalog No. ABIN7161663
  • Target See all NMRAL1 Antibodies
    NMRAL1 (NmrA-Like Family Domain Containing 1 (NMRAL1))
    Binding Specificity
    • 7
    • 1
    • 1
    • 1
    AA 1-299
    Reactivity
    • 11
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 10
    • 2
    Rabbit
    Clonality
    • 12
    Polyclonal
    Conjugate
    • 9
    • 1
    • 1
    • 1
    This NMRAL1 antibody is conjugated to FITC
    Application
    Please inquire
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human NmrA-like family domain-containing protein 1 protein (1-299AA)
    Isotype
    IgG
    Top Product
    Discover our top product NMRAL1 Primary Antibody
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    NMRAL1 (NmrA-Like Family Domain Containing 1 (NMRAL1))
    Alternative Name
    NMRAL1 (NMRAL1 Products)
    Synonyms
    HSCARG antibody, SDR48A1 antibody, 1110025F24Rik antibody, AI256624 antibody, RGD1311451 antibody, NmrA like redox sensor 1 antibody, NmrA-like family domain containing 1 antibody, NMRAL1 antibody, Nmral1 antibody
    Background

    Background: Redox sensor protein. Undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP(+) levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds argininosuccinate synthase (ASS1), the enzyme involved in nitric oxide synthesis. Association with ASS1 impairs its activity and reduces the production of nitric oxide, which subsecuently prevents apoptosis. Under normal NADPH concentrations, the protein is found as a dimer and hides the binding site for ASS1. The homodimer binds one molecule of NADPH. Has higher affinity for NADPH than for NADP(+). Binding to NADPH is necessary to form a stable dimer.

    Aliases: FLJ25918 antibody, HSCARG antibody, NmrA like family domain containing 1 antibody, NmrA like family domain containing protein 1 antibody, NmrA-like family domain-containing protein 1 antibody, NMRAL1 antibody, NMRL1_HUMAN antibody, SDR48A1 antibody

    UniProt
    Q9HBL8
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