NLRX1 antibody (AA 45-205) (Biotin)

Catalog No. ABIN7161656

Product Details anti-NLRX1 Antibody (Biotin)

Target: NLRX1 (NLR Family Member X1 (NLRX1))

Binding Specificity: AA 45-205

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRX1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human NLR family member X1 protein (45-205AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NLRX1

Target: NLRX1 (NLR Family Member X1 (NLRX1))

Alternative Name: NLRX1 (NLRX1 Products)

Background:

Background: Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Has no inhibitory function on NF-Kappa-B and type 1 interferon signaling pathways, but enhances NF-Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313).

Aliases: Caterpiller protein 11.3 antibody, CLR11.3 antibody, DLNB26 antibody, FLJ21478 antibody, MGC131937 antibody, MGC21025 antibody, NLR family member X1 antibody, NLR family, X1 antibody, Nlrx1 antibody, NLRX1_HUMAN antibody, NOD-like receptor X1 antibody, NOD26 antibody, NOD5 antibody, NOD9 antibody, Nucleotide-binding oligomerization domain protein 26 antibody, Nucleotide-binding oligomerization domain protein 5 antibody, Nucleotide-binding oligomerization domain protein 9 antibody, nucleotide-binding oligomerization domain, leucine rich repeat containing X1 antibody, Protein Caterpiller 11.3 antibody

UniProt: Q86UT6

Pathways: SARS-CoV-2 Protein Interactome