NMNAT3 antibody (AA 1-215)

Catalog No. ABIN7161584

Product Details anti-NMNAT3 Antibody

Target: NMNAT3 (Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3))

Binding Specificity: AA 1-215

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NMNAT3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 protein (1-215AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NMNAT3

Target: NMNAT3 (Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3))

Alternative Name: NMNAT3 (NMNAT3 Products)

Synonyms: PNAT-3 antibody, PNAT3 antibody, 4933408N02Rik antibody, nicotinamide nucleotide adenylyltransferase 3 antibody, si:ch73-170l17.1 antibody, Nmnat3 antibody, NMNAT3 antibody, si:ch73-170l17.1 antibody

Background:

Background: Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form, nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+. For the pyrophosphorolytic activity, can use NAD (+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP+, NADPH and NAADP+. Protects against axonal degeneration following injury.

Aliases: NaMN adenylyltransferase 3 antibody, Nicotinamide mononucleotide adenylyltransferase 3 antibody, Nicotinamide nucleotide adenylyltransferase 3 antibody, Nicotinate-nucleotide adenylyltransferase 3 antibody, NMN adenylyltransferase 3 antibody, NMNA3_HUMAN antibody, NMNAT 3 antibody, Nmnat3 antibody, PNAT 3 antibody, PNAT-3 antibody, PNAT3 antibody, Pyridine nucleotide adenylyltransferase 3 antibody

UniProt: Q96T66