NAMPT antibody (AA 1-280)

Catalog No. ABIN7161572

Product Details anti-NAMPT Antibody

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Binding Specificity: AA 1-280

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAMPT antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Nicotinamide phosphoribosyltransferase protein (1-280AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IP:1:200-1:2000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NAMPT

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Alternative Name: NAMPT (NAMPT Products)

Synonyms: 1110035O14Rik antibody, PBEF antibody, PBEF1 antibody, VF antibody, VISFATIN antibody, AI314458 antibody, AI480535 antibody, NAmPRTase antibody, Pbef antibody, Pbef1 antibody, Visfatin antibody, visfatin antibody, pbef antibody, pbef1 antibody, nicotinamide phosphoribosyltransferase antibody, Nicotinamide phosphoribosyltransferase antibody, nicotinamide phosphoribosyltransferase S homeolog antibody, NAMPT antibody, Nampt antibody, nampt antibody, Smon_0680 antibody, Mrub_2845 antibody, Cseg_3704 antibody, BC1002_3997 antibody, Ftrac_2686 antibody, Varpa_5681 antibody, Celal_3900 antibody, Deima_0880 antibody, BC1001_3724 antibody, Celly_1696 antibody, Clole_1542 antibody, Tsp_05934 antibody, nampt.S antibody

Background:

Background: Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression .

Aliases: 1110035O14Rik antibody, AI314458 antibody, AI480535 antibody, DKFZP666B131 antibody, EC 2.4.2.12 antibody, MGC117256 antibody, NAmPRTase antibody, Nampt antibody, NAMPT_HUMAN antibody, Nicotinamide phosphoribosyltransferase antibody, PBEF 1 antibody, PBEF antibody, PBEF1 antibody, Pre B cell colony enhancing factor 1 antibody, Pre B cell colony enhancing factor antibody, Pre B cell enhancing factor antibody, Pre-B cell-enhancing factor antibody, Pre-B-cell colony-enhancing factor 1 antibody, VF antibody, Visfatin antibody

UniProt: P43490