NKIRAS1 antibody (AA 1-192) (Biotin)

Catalog No. ABIN7161531

Product Details anti-NKIRAS1 Antibody (Biotin)

Target: NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

Binding Specificity: AA 1-192

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKIRAS1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human NF-kappa-B inhibitor-interacting Ras-like protein 1 protein (1-192AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NKIRAS1

Target: NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

Alternative Name: NKIRAS1 (NKIRAS1 Products)

Synonyms: NKIRAS1 antibody, KBRAS1 antibody, kappaB-Ras1 antibody, zgc:92823 antibody, kbras1 antibody, 2400004O09Rik antibody, NFKB inhibitor interacting Ras like 1 antibody, NFKB inhibitor interacting Ras-like 1 antibody, NFKB inhibitor interacting Ras-like 1 S homeolog antibody, NFKB inhibitor interacting Ras-like protein 1 antibody, NKIRAS1 antibody, nkiras1 antibody, nkiras1.S antibody, Nkiras1 antibody

Background:

Background: Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.

Aliases: 2400004O09Rik antibody, I kappa B interacting Ras like protein 1 antibody, I-kappa-B-interacting Ras-like protein 1 antibody, Kappa B Ras 1 antibody, Kappa B Ras protein 1 antibody, Kappa B-Ras protein 1 antibody, KappaB Ras1 antibody, KappaB-Ras1 antibody, KBRAS 1 antibody, KBRAS1 antibody, KBRS1_HUMAN antibody, NF kappa B inhibitor interacting Ras like protein 1 antibody, NF-kappa-B inhibitor-interacting Ras-like protein 1 antibody, NFKB inhibitor interacting Ras like 1 antibody, NFKB inhibitor interacting Ras like protein 1 antibody, NKIRAS 1 antibody, nkiras1 antibody

UniProt: Q9NYS0