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ASAH2 antibody (AA 255-506)

ASAH2 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7161486
  • Target See all ASAH2 Antibodies
    ASAH2 (N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2))
    Binding Specificity
    • 9
    • 8
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    AA 255-506
    Reactivity
    • 32
    • 14
    • 5
    Human
    Host
    • 33
    • 1
    Rabbit
    Clonality
    • 34
    Polyclonal
    Conjugate
    • 11
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ASAH2 antibody is un-conjugated
    Application
    • 20
    • 19
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human, Rat
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Neutral ceramidase protein (255-506AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:500,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    ASAH2 (N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2))
    Alternative Name
    ASAH2 (ASAH2 Products)
    Synonyms
    BCDase antibody, HNAC1 antibody, LCDase antibody, N-CDase antibody, NCDase antibody, AI585898 antibody, N-acylsphingosine amidohydrolase 2 antibody, ASAH2 antibody, Asah2 antibody
    Background

    Background: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5. Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1-phosphate. Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract.

    Aliases: Acylsphingosine deacylase 2 antibody, AI585898 antibody, ASAH2 antibody, ASAH2_HUMAN antibody, BCDase antibody, hCD antibody, HNAC1 antibody, LCDase antibody, MGC129777 antibody, mitochondrial ceramidase antibody, N acylsphingosine amidohydrolase (non lysosomal ceramidase) 2 antibody, N acylsphingosine amidohydrolase 2 antibody, N CDase antibody, N-acylsphingosine amidohydrolase 2 antibody, N-CDase antibody, NCDase antibody, Neutral ceramidase soluble form antibody, Non lysosomal ceramidase antibody, Non-lysosomal ceramidase antibody

    UniProt
    Q9NR71
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