ASAH2 antibody (AA 255-506)
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- Target See all ASAH2 Antibodies
- ASAH2 (N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2))
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Binding Specificity
- AA 255-506
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ASAH2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Human, Rat
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Neutral ceramidase protein (255-506AA)
- Isotype
- IgG
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- Application Notes
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:500,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- ASAH2 (N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2))
- Alternative Name
- ASAH2 (ASAH2 Products)
- Synonyms
- BCDase antibody, HNAC1 antibody, LCDase antibody, N-CDase antibody, NCDase antibody, AI585898 antibody, N-acylsphingosine amidohydrolase 2 antibody, ASAH2 antibody, Asah2 antibody
- Background
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Background: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5. Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1-phosphate. Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract.
Aliases: Acylsphingosine deacylase 2 antibody, AI585898 antibody, ASAH2 antibody, ASAH2_HUMAN antibody, BCDase antibody, hCD antibody, HNAC1 antibody, LCDase antibody, MGC129777 antibody, mitochondrial ceramidase antibody, N acylsphingosine amidohydrolase (non lysosomal ceramidase) 2 antibody, N acylsphingosine amidohydrolase 2 antibody, N CDase antibody, N-acylsphingosine amidohydrolase 2 antibody, N-CDase antibody, NCDase antibody, Neutral ceramidase soluble form antibody, Non lysosomal ceramidase antibody, Non-lysosomal ceramidase antibody
- UniProt
- Q9NR71
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