GPM6A antibody (AA 149-213) (HRP)

Catalog No. ABIN7161373

Product Details anti-GPM6A Antibody (HRP)

Target: GPM6A (Glycoprotein M6A (GPM6A))

Binding Specificity: AA 149-213

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPM6A antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Neuronal membrane glycoprotein M6-a protein (149-213AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GPM6A

Target: GPM6A (Glycoprotein M6A (GPM6A))

Alternative Name: GPM6A (GPM6A Products)

Synonyms: GPM6 antibody, M6A antibody, Gpm6 antibody, M6a antibody, EMA antibody, GPM6A antibody, gpm6a antibody, MGC145278 antibody, DMbeta/M6a antibody, gpm6a-A antibody, wu:fj36c01 antibody, zgc:77575 antibody, DMbeta2 antibody, gm6a antibody, glycoprotein M6A antibody, glycoprotein m6a antibody, glycoprotein M6A L homeolog antibody, glycoprotein M6Aa antibody, glycoprotein M6Ab antibody, GPM6A antibody, Gpm6a antibody, gpm6a antibody, gpm6a.L antibody, gpm6aa antibody, gpm6ab antibody

Background:

Background: Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs), enhances internalization and recycling of mu-type opioid receptor.

Aliases: GPM6A antibody, GPM6A_HUMAN antibody, M6a antibody, Neuronal membrane glycoprotein M6-a antibody, Neuronal membrane glycoprotein M6-a, antibody

UniProt: P51674