Neuroglobin antibody (AA 1-151)

Catalog No. ABIN7161310

Product Details anti-Neuroglobin Antibody

Target: Neuroglobin (NGB)

Binding Specificity: AA 1-151

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neuroglobin antibody is un-conjugated

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Neuroglobin protein (1-151AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Neuroglobin

Target: Neuroglobin (NGB)

Alternative Name: NGB (NGB Products)

Synonyms: NGB antibody, ngb antibody, neuroglobin antibody, neuroglobin L homeolog antibody, NGB antibody, Ngb antibody, ngb antibody, ngb.L antibody

Background:

Background: Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis.

Aliases: Neuroglobin antibody, NGB antibody, NGB_HUMAN antibody

UniProt: Q9NPG2