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Neurexin 1 antibody (AA 31-310)

NRXN1 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7161215
  • Target See all Neurexin 1 (NRXN1) Antibodies
    Neurexin 1 (NRXN1)
    Binding Specificity
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-310
    Reactivity
    • 28
    • 10
    • 9
    • 1
    • 1
    Human
    Host
    • 25
    • 3
    • 2
    • 1
    Rabbit
    Clonality
    • 29
    • 2
    Polyclonal
    Conjugate
    • 19
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Neurexin 1 antibody is un-conjugated
    Application
    • 16
    • 16
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Cross-Reactivity
    Human
    Purification
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Neurexin-1 protein (31-310AA)
    Isotype
    IgG
    Top Product
    Discover our top product NRXN1 Primary Antibody
  • Application Notes
    Recommended dilution: WB:1:1000-1:5000,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Neurexin 1 (NRXN1)
    Alternative Name
    NRXN1 (NRXN1 Products)
    Synonyms
    Hs.22998 antibody, PTHSL2 antibody, SCZD17 antibody, CG7050 antibody, CT21808 antibody, Dmel\\CG7050 antibody, Nrx antibody, Nrx1 antibody, dnrx antibody, dnrx-1 antibody, nrx antibody, Nrxn1b antibody, NRXN1 antibody, Nrx-1 antibody, GB13455 antibody, GB18754 antibody, 1700062G21Rik antibody, 9330127H16Rik antibody, A230068P09Rik antibody, mKIAA0578 antibody, neurexin 1 antibody, Neurexin 1 antibody, neurexin I antibody, neurexin 1b antibody, neurexin 1a antibody, NRXN1 antibody, Nrx-1 antibody, Nrxn1 antibody, nrxn1 antibody, nrxn1b antibody, nrxn1a antibody
    Background

    Background: Cell surface protein involved in cell-cell-interactions, exocytosis of secretory granules and regulation of signal transmission. Function is isoform-specific. Alpha-type isoforms have a long N-terminus with six laminin G-like domains and play an important role in synaptic signal transmission. Alpha-type isoforms play a role in the regulation of calcium channel activity and Ca(2+)-triggered neurotransmitter release at synapses and at neuromuscular junctions. They play an important role in Ca(2+)-triggered exocytosis of secretory granules in pituitary gland. They may effect their functions at synapses and in endocrine cells via their interactions with proteins from the exocytotic machinery. Likewise, alpha-type isoforms play a role in regulating the activity of postsynaptic NMDA receptors, a subtype of glutamate-gated ion channels. Both alpha-type and beta-type isoforms may play a role in the formation or maintenance of synaptic junctions via their calcium-dependent interactions (via the extracellular domains) with neuroligin family members, CBLN1 or CBLN2. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Alpha-type isoforms were first identified as receptors for alpha-latrotoxin from spider venom (By similarity).

    Aliases: DKFZp313P2036 antibody, FLJ35941 antibody, Hs.22998 antibody, KIAA0578 antibody, Neurexin 1 alpha antibody, Neurexin 1 beta antibody, Neurexin I-alpha antibody, Neurexin-1 antibody, Neurexin-1-alpha antibody, NRX1A_HUMAN antibody, NRXN1 antibody, PTHSL2 antibody, SCZD17 antibody

    UniProt
    Q9ULB1
    Pathways
    Synaptic Membrane, Skeletal Muscle Fiber Development
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