UNC5D antibody (AA 90-212) (Biotin)

Catalog No. ABIN7161188

Product Details anti-UNC5D Antibody (Biotin)

Target: UNC5D (Unc-5 Homolog D (UNC5D))

Binding Specificity: AA 90-212

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UNC5D antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Netrin receptor UNC5D protein (90-212AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for UNC5D

Target: UNC5D (Unc-5 Homolog D (UNC5D))

Alternative Name: UNC5D (UNC5D Products)

Synonyms: UNC5D antibody, PRO34692 antibody, Unc5h4 antibody, D930029E11Rik antibody, mKIAA1777 antibody, unc-5 netrin receptor D antibody, unc-5 homolog D (C. elegans) antibody, Unc5d antibody, UNC5D antibody, unc5d antibody

Background:

Background: Receptor for the netrin NTN4 that promotes neuronal cell survival (By similarity). Plays a role in cell-cell adhesion and cell guidance. Receptor for netrin involved in cell migration. Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding (By similarity). May play a role in apoptosis in response to DNA damage (PubMed:24691657). It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (PubMed:24519068). Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell (By similarity).

Aliases: UNC5D antibody, KIAA1777 antibody, UNC5H4 antibody, UNQ6012/PRO34692 antibody, Netrin receptor UNC5D antibody, Protein unc-5 homolog 4 antibody, Protein unc-5 homolog D antibody

UniProt: Q6UXZ4