NDN antibody (AA 1-98)

Catalog No. ABIN7161105

Product Details anti-NDN Antibody

Target: NDN (Necdin Homolog (Mouse) (NDN))

Binding Specificity: AA 1-98

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDN antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Necdin protein (1-98AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NDN

Target: NDN (Necdin Homolog (Mouse) (NDN))

Alternative Name: NDN (NDN Products)

Synonyms: LOC574323 antibody, AI528698 antibody, Peg6 antibody, NDN antibody, HsT16328 antibody, PWCR antibody, necdin, MAGE family member antibody, necdin antibody, NDN antibody, Ndn antibody

Background:

Background: Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle-promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Functions also as transcription factor and binds directly to specific guanosine-rich DNA sequences (By similarity).

Aliases: HsT16328 antibody, NDN antibody, NECD_HUMAN antibody, Necdin antibody, Necdin homolog antibody, Necdin MAGE family member antibody, necdin related protein antibody, PWCR antibody

UniProt: Q99608

Pathways: Neurotrophin Signaling Pathway