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NCR3 antibody (AA 19-135) (FITC)

NCR3 Reactivity: Human Host: Rabbit Polyclonal FITC
Catalog No. ABIN7161082
  • Target See all NCR3 Antibodies
    NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
    Binding Specificity
    • 16
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 19-135
    Reactivity
    • 55
    • 14
    • 3
    • 2
    Human
    Host
    • 48
    • 9
    Rabbit
    Clonality
    • 46
    • 11
    Polyclonal
    Conjugate
    • 27
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NCR3 antibody is conjugated to FITC
    Application
    Please inquire
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Natural cytotoxicity triggering receptor 3 protein (19-135AA)
    Isotype
    IgG
    Top Product
    Discover our top product NCR3 Primary Antibody
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
    Alternative Name
    NCR3 (NCR3 Products)
    Synonyms
    MGC133750 antibody, 1C7 antibody, CD337 antibody, LY117 antibody, MALS antibody, NKp30 antibody, Nkp30 antibody, natural cytotoxicity triggering receptor 3 antibody, NCR3 antibody, Ncr3 antibody
    Background

    Background: Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation.

    Aliases: 1C7 antibody, Activating natural killer receptor p30 antibody, Activating NK A1 receptor antibody, CD337 antibody, CD337 antigen antibody, LY117 antibody, Lymphocyte antigen 117 antibody, MALS antibody, Natural cytotoxicity triggering receptor 3 antibody, Natural killer cell p30 related protein antibody, Natural killer cell p30-related protein antibody, Ncr3 antibody, NCTR3_HUMAN antibody, NK-p30 antibody, NKp30 antibody

    UniProt
    O14931
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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