NCR3 antibody (AA 19-135) (FITC)
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- Target See all NCR3 Antibodies
- NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
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Binding Specificity
- AA 19-135
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NCR3 antibody is conjugated to FITC
- Application
- Please inquire
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Natural cytotoxicity triggering receptor 3 protein (19-135AA)
- Isotype
- IgG
- Top Product
- Discover our top product NCR3 Primary Antibody
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
- Alternative Name
- NCR3 (NCR3 Products)
- Synonyms
- MGC133750 antibody, 1C7 antibody, CD337 antibody, LY117 antibody, MALS antibody, NKp30 antibody, Nkp30 antibody, natural cytotoxicity triggering receptor 3 antibody, NCR3 antibody, Ncr3 antibody
- Background
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Background: Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation.
Aliases: 1C7 antibody, Activating natural killer receptor p30 antibody, Activating NK A1 receptor antibody, CD337 antibody, CD337 antigen antibody, LY117 antibody, Lymphocyte antigen 117 antibody, MALS antibody, Natural cytotoxicity triggering receptor 3 antibody, Natural killer cell p30 related protein antibody, Natural killer cell p30-related protein antibody, Ncr3 antibody, NCTR3_HUMAN antibody, NK-p30 antibody, NKp30 antibody
- UniProt
- O14931
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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