NACA2 antibody (AA 1-215) (Biotin)

Catalog No. ABIN7161052

Product Details anti-NACA2 Antibody (Biotin)

Target: NACA2 (NACa2) (Nascent Polypeptide-Associated Complex alpha Subunit 2 (NACa2))

Binding Specificity: AA 1-215

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NACA2 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Nascent polypeptide-associated complex subunit alpha-2 protein (1-215AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NACA2

Target: NACA2 (NACa2) (Nascent Polypeptide-Associated Complex alpha Subunit 2 (NACa2))

Alternative Name: NACA2 (NACa2 Products)

Synonyms: ANAC antibody, NACAL antibody, nascent polypeptide associated complex alpha subunit 2 antibody, NACA2 antibody

Background:

Background: Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites).

Aliases: NACA2 antibody, NACAL antibody, Nascent polypeptide-associated complex subunit alpha-2 antibody, Alpha-NAC-like antibody, Hom s 2.01 antibody, Nascent polypeptide-associated complex subunit alpha-like antibody, NAC-alpha-like antibody

UniProt: Q9H009