NANOS3 antibody (AA 21-192)

Catalog No. ABIN7161039

Product Details anti-NANOS3 Antibody

Target: NANOS3 (Nanos Homolog 3 (NANOS3))

Binding Specificity: AA 21-192

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NANOS3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Nanos homolog 3 protein (21-192AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NANOS3

Target: NANOS3 (Nanos Homolog 3 (NANOS3))

Alternative Name: NANOS3 (NANOS3 Products)

Synonyms: NANOS1L antibody, NOS3 antibody, nos3 antibody, cb725 antibody, nanos antibody, nanos1 antibody, nos1 antibody, nanos C2HC-type zinc finger 3 antibody, nanos homolog 3 (Drosophila) antibody, nanos homolog 3 antibody, NANOS3 antibody, Nanos3 antibody, nanos3 antibody

Background:

Background: Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax-dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis.

Aliases: NANO3_HUMAN antibody, Nanos homolog 3 antibody, NANOS3 antibody, NOS-3 antibody, Nos3 antibody

UniProt: P60323

Pathways: ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling