Nanos Homolog 1 antibody (AA 1-292) (Biotin)

Catalog No. ABIN7161032

Product Details anti-Nanos Homolog 1 Antibody (Biotin)

Target: Nanos Homolog 1 (NANOS1)

Binding Specificity: AA 1-292

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nanos Homolog 1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Nanos homolog 1 protein (1-292AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Nanos Homolog 1

Target: Nanos Homolog 1 (NANOS1)

Alternative Name: NANOS1 (NANOS1 Products)

Synonyms: NOS1 antibody, nanos1 antibody, fb76c12 antibody, wu:fb93h11 antibody, wu:fb98e07 antibody, wu:fq21a10 antibody, Xcat-2 antibody, nos1 antibody, xnos1 antibody, xcat-2 antibody, LOC100144352 antibody, NANOS1A antibody, nanos C2HC-type zinc finger 1 antibody, nanos homolog 1 antibody, nanos homolog 1 (Drosophila) antibody, nanos homolog 1 L homeolog antibody, Nanos homolog 1 antibody, nanos1 antibody, NANOS1 antibody, nanos1 antibody, Nanos1 antibody, nanos1.L antibody, nano1 antibody, nanos1a antibody

Background:

Background: May act as a translational repressor which regulates translation of specific mRNAs by forming a complex with PUM2 that associates with the 3\'-UTR of mRNA targets. Capable of interfering with the proadhesive and anti-invasive functions of E-cadherin. Up-regulates the production of MMP14 to promote tumor cell invasion.

Aliases: EC Rep1a antibody, EC_Rep1a antibody, NANO1_HUMAN antibody, NANOS 1 antibody, Nanos homolog 1 (Drosophila) antibody, Nanos homolog 1 antibody, Nanos Homologue 1 (NANOS1) antibody, NANOS1 antibody, Nos 1 antibody, NOS-1 antibody, Nos1 antibody, OTTHUMP00000046853 antibody, Rep 1a antibody, Rep1a antibody

UniProt: Q8WY41

Pathways: Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction